Scientific name for vitamin E–tocopherol was adopted as vitamin E supported fertility. In Greek, tokos means childbirth while phero means to bring forth.
Vitamin E was discovered in wheat germ oil.
Vitamin E was found to protect people from coronary heart disease
A vitamin E compound was isolated from a rubber plant, Havea brasiliensis and it was named “Tocotrienols”.
Vitamin E recognized as an essential nutrient officially by the Food and Nutrition Board of the National Academy of Sciences.
Tocotrienol (T3) from barley showed decreased rate of cholesterol synthesis, total and LDL (low-density lipoprotein) when feeding to chicken.
T3 demonstrated hypocholesterolemic effects in an animal and 2 human studies
T3 derived from palm oil exhibited anti-cancer effects in EBV (Epstein – Barr virus) human lymphoblastoid cells.
T3 from palm oil showed antioxidant effects & attenuate carotid atherosclerosis
Nanomolar concentrations of T3 inhibited glutamate-induced neuronal cell death, by Prof Sen.
A bio-enhanced delivery system (SupraBio® System) for consistent and optimal absorption of T3 was developed.
National Institute of Health (NIH)-funded neuroprotective studies (in vitro, in vivo & clinical studies) led by Prof Sen commenced.
T3 demonstrated neuroprotection by antioxidant-independent mechanism.
First clinical study – SupraBio® System on hair growth
First clinical study- SupraBio® System on heart health (arterial compliance)
First T3 conference (Las Vegas) organized by Malaysian Palm Oil Board (MPOB).
First clinical study on SupraBio® System on Liver
Health (Fatty Liver/NAFLD)
First clinical study- SupraBio® System attenuates white matter lesion progression (pre-stroke symptom).