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Red palm oil fruit has been in the news a lot lately as there are incredible health benefits associated to it. Consumers are accepting red palm fruit oil with positive feedbacks as well.
ExcelVite has been exhibiting for the past 10 years and receiving tremendous response from customers especially on the robust science on neuroprotection. NIH(National Institute of Health)-funded neuroprotection studies conducted at Ohio State University Medical Center have been started since 2000 and tocotrienol shows stroke induced injuries attenuation and this is significantly important for patients with hypertension. If there are circulating tocotrienols in the brain of hypertensive patients, they might have protected with cerebra small vessel disease.
These neuroprotection studies are led by Dr. Chandan Sen, from Ohio State University and has proven neuroprotection on post-stroke injuries and also new neuronal growth around the brain. Tocotrienol also helps in attenuating non-alcoholic fatty liver disease (NAFLD). Nearly 30% of Americans are diagnosed with fatty liver without realizing it because NAFLD is asymptomatic but there is still no cure to date. A study with 68 NAFLD patients are randomized to receive SupraBio™ supplementation or placebo. Results show that about 67% of NAFLD patients on SupraBio™ demonstrated improved condition, and about 50% of SupraBio™-supplemented patients are have NAFLD remission. Hence, this opens up a whole new opportunity for tocotrienol with regards to liver health.
When choosing for dietary supplements, it is important to consume the dietary supplements that are used in human clinical studies. The main product of tocotrienol that are used in human clinical studies are SupraBio™ – a patented, bioenhanced full spectrum tocotrienol complex.
Below are some of the relevant references:
NIH-funded neuroprotection studies
- Sen C.K., et.al (2000). Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells. J Biol Chem.
- Khanna, S., et.al (2003). Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration. J Biol Chem.
- Khanna, S., et.al (2010). Nanomolar vitamin E alpha-tocotrienol inhibits glutamate-induced activation of phospholipase A2 and causes neuroprotection. J Neurochem.
- Khanna S., et.al (2013). Loss of miR-29b following acute ischemic stroke contributes to neural cell death and infarct size. J Cereb Blood Flow Metab.
- Rink, C. et.al (2011). Tocotrienol vitamin E protects against preclinical canine ischemic stroke by inducing arteriogenesis. J Cereb Blood Flow Metab.
- https://clinicaltrials.gov/ct2/show/NCT01578629
NAFLD
Arguillas, M., et.al (2013). http://www.excelvite.com/wp-content/uploads/2015/04/EFFECT1.pdf
SupraBio™